QMessage Monitor can invoke escalation procedures if a message is still outstanding after a period of time or meets other criteria that you've determined.
There is an escalation parameter on the auto-reply specification. You define how much time should elapse before an escalation takes place. This can be overridden by the operator.
An acknowledgment from the central console stops any escalation for a period of time, after which the message reverts to an inquiry message and resets the escalation procedures. This lets busy operators acknowledge some problems while working on others that have higher priority.